About

Prana Therapies is a clinical-stage biotechnology company pioneering a new generation of multispecific antibodies designed to deliver best-in-disease therapies across a broad range of diseases.

Our proprietary INSPIRE platform combines complementary therapeutic mechanisms into a single drug, to create differentiated medicines with the potential for enhanced efficacy and infrequent dosing.

Prana is advancing a wholly owned pipeline of multispecific therapeutics, initially focused on respiratory and dermatologic diseases, with discovery-stage programs expanding across therapeutic areas.

platform

Engineering multispecifics for the whole product profile

INSPIRE is Prana's proprietary multispecific antibody platform, designed to overcome key limitations of conventional multispecific formats and create medicines with the efficacy, pharmacokinetics, and drug-like properties needed to deliver a differentiated product profile.

INSPIRE combines complementary therapeutic mechanisms within a single, fully IgG-based molecule. Our candidates are designed for enhanced efficacy, extended half-life, low immunogenicity, high-concentration subcutaneous delivery, and infrequent, at-home dosing, while maintaining favorable stability and manufacturability.

The platform is modular and scalable, enabling Prana to generate differentiated candidates across targets and therapeutic areas. PRA-216, our lead clinical program, provides the first clinical validation of INSPIRE.

newsroom

Latest from Prana

Explore the latest company news, scientific presentations, and publications from Prana Therapies.

SepT 8
2026

Prana Therapies Announces Positive Phase 1 Results for PRA-216, a Novel IL-4Rα/TSLP Bispecific Antibody, Supporting Its Potential Best-in-Disease Profile and Providing the First Clinical Validation of Prana’s INSPIRE Multispecific Platform

Prana Therapies, Inc. (“Prana”), a clinical-stage biotechnology company pioneering next generation half-life-extended multispecific antibodies designed to deliver best-in-disease therapies, today announced positive Phase 1 results for PRA-216, its lead clinical program and a  fully human, half-life-extended bispecific antibody developed on Prana’s proprietary INSPIRE platform.

SepT 8
2026

ERA 2026 Poster: PRA-216 Phase 1 Results

Prana Therapies presents late-breaker poster at The ERS Congress 2026 in Barcelona, Spain.

team

Built by experienced drug developers

Prana brings together an experienced team of scientists, drug developers, and industry leaders with a track record of discovering and advancing innovative therapeutics from concept through clinical development.

Leadership Team

Sheila Gujrathi
Founder & CEO
Ryan Sullivan
Chief Scientific Officer
Hector Ortega
Chief Medical Officer
Christina Trout
VP Corporate Development
Miguel Sanjuan
Founder & Strategic Scientific Advisor

contact

Connect with Prana

For partnering, media, and other inquiries, please contact us at info@pranatherapies.com

Prana Therapies, Inc.
San Diego, California